Dietary Fat, but Not Protein or Carbohydrate, Regulates Energy Intake and Causes Adiposity in MiceHighlights
•Energy intake was linked only to dietary fat levels and not protein or sucrose
•Adiposity increased with increasing fat content to 60% but thereafter declined
•Hypothalamic hunger pathways were unresponsive to dietary protein content
•Dopamine, opioid, and serotonin pathways were all stimulated by fat intake
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